Dissertation Defense: Hao Yu  Add To Calendar

  • Date(s): Friday, 1/17 10:00 AM to Friday, 1/17 1:00 PM
  • Campus Address: 2214 SES SES Science and Engineering South
  • Email: jnell@uic.edu
This research is devoted to studies of the influence of an externally controlled electric potential difference on Gibbs monolayers of 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine (SOPC), as well as its influence on the binding of the C2 domain of cytosolic phospholipase-A2 (cPLA2 -C2) protein to the SOPC monolayer. X-ray reflectivity, molecular dynamics (MD) simulations and electrochemical methods are used to gather microscopic and macroscopic information about the ordering, orientation, and binding configuration of the molecules on the electric potential difference or membrane potential.